Venture success

A Case-connected medical device company is giving the university’s new business accelerator, the 11000 Cedar Startup Incubator, one of its first success stories.

Neuronoff, Inc., which specializes in nerve stimulation for pain relief, in October announced attracting $4.5 million in fresh investment in an oversubscribed funding round. The infusion of cash will help the young company advance its product toward FDA clearance and commercial launch.

“This funding validates our investors’ confidence in bringing elegant, needle-based neuromodulation to future patients,” said Manfred Franke, PhD ’14, the co-founder and CEO of Neuronoff. Another co-founder is Andrew Shoffstall,PhD ’13, an assistant professor of bio-medical engineering at the Case School of Engineering.

Their nine-year-old company develops pain management treatments that use electrical pulses to block nerve impulses, technology springing from their research in Case labs. Its treatment platform, called Injectrode, provides a simpler, less-invasive implant than those used in other neurostimulation therapies, the founders say.

Neuronoff is a prominent tenant of 11000 Cedar, the former BioEnterprise building, which CWRU is redeveloping into a science-friendly business accelerator. The four-story, 80,000 square-foot complex offers startup space, wet and dry labs, and shared scientific equipment. It was featured in the spring 2025 issue of Case Alumnus.

For information on 11000 Cedar and membership opportunities, email Andrew Cornwell at startups@case.edu.